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 ALL TIME TOP 10 BY F1000 FACTOR | ALL OF MEDICINE | calculated on 2 September 2010

All Time Top 10 By F1000 Factors are generated every day using papers added to F1000 Medicine since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 12.6
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
Controversial
Refutation
 Intensive versus conventional glucose control in critically ill patients.
Finfer S, Chittock DR, …, Robinson BG, Ronco JJ
N Engl J Med 2009 Mar 26 360:1283-97 [abstract on PubMed] [related articles] [order article]
Selected by | Benedikt Preckel / Walter Hasibeder / Jean-Charles Preiser / Nicholas Barrett / Nigel Webster / Emine Aysu Salviz and Alain Vuylsteke / Jacobo Sellares and Antoni Torres / Greg Martin / Patrice Forget and Marc De Kock / John Laffey / Jose Pascual and Babak Sarani / Priya Shah and Seth Field / Bruce Bistrian / Ashish Sinha and John Augoustides / Regina Schumann and Manfred Seeberger
First evaluation 31 Mar 2009 | Latest evaluation 11 Aug 2009
 
2
Exceptional
F1000 Factor 12.4

Confirmation
New Finding
 Dabigatran versus warfarin in patients with atrial fibrillation.
Connolly SJ, Ezekowitz MD, …, Wallentin L, RE-LY Steering Committee and Investigators
N Engl J Med 2009 Sep 17 361(12):1139-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Ruff / Rakesh Gopinathannair and Brian Olshansky / José A García Donaire and Luis Ruilope / Wilbert Aronow / Sung Ham and Fred Weaver / Fernando Testai and Philip Gorelick / Guy Amit and I Eli Ovsyshcher / Anna Maria Choy and Chim Lang / Heather Bloom / Harri Jenkins / Wolfgang Schoels / Ashfaq Shuaib / Aleksandra Pikula and Carlos Kase / Angela Adams, Jeffrey Veluz and Megan Leary
First evaluation 7 Sep 2009 | Latest evaluation 18 Jan 2010
 
3
Exceptional
F1000 Factor 11.5
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
Controversial
Refutation
 Anesthesia awareness and the bispectral index.
Avidan MS, Zhang L, …, Jacobsohn E, Evers AS
N Engl J Med 2008 Mar 13 358(11):1097-108 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vesna Jevtovic-Todorovic / Philippa Newfield / Beverley Orser / Emery Brown / Harald Groeben / Benedikt Pannen / Manfred Seeberger / Alain Borgeat / Lynda Wells / Dhanesh Gupta / Serene Leo and Alex Sia / Paul Barash / Michael O'Connor / Masahiko Kawaguchi
Dissenters | Elise Sarton and Albert Dahan / Seppo Alahuhta and Ville Jantti
Author Response | Avidan MS, Zhang L, Burnside BA, Finkel KJ, Searleman AC, Selvidge JA, Saager L, Turner MS, Rao S, Bottros M, Hantler C, Jacobsohn E, Evers AS. B-Unaware Trial Group / Avidan et al. [2] / Avidan et al. [3] / Avidan et al. [4] / Avidan et al. [5] / Avidan et al. [13] / Avidan et al. [12] / Avidan et al. [6] / Avidan et al. [7] / Avidan et al. [14] / Avidan et al. [8] / Avidan et al. [9] / Avidan et al. [10] / Avidan et al. [11]
First evaluation 18 Mar 2008 | Latest evaluation 11 Jun 2008

 
4
Exceptional
F1000 Factor 11.2

Confirmation
Hypothesis
New Finding
Tech Advance
 Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
Binshtok AM, Bean BP, Woolf CJ
Nature 2007 Oct 4 449(7162):607-10 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Misha Perouansky / Nanna Finnerup / Hugh Hemmings / Emery Brown / Helge Eilers / David Archer / Daniel Vilceanu and Cheryl Stucky / Michael Schaefer
First evaluation 23 Oct 2007 | Latest evaluation 13 Mar 2008

 
5
Exceptional
F1000 Factor 10.7
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
 Treatment of hypertension in patients 80 years of age or older.
Beckett NS, Peters R, …, Bulpitt CJ, HYVET Study Group
N Engl J Med 2008 May 1 358(18):1887-98 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dharam Kumbhani and Deepak Bhatt / Ramachandran S. Vasan / Jerome Fleg / Annemarie Hennessy / Ernesto Schiffrin / Wilbert Aronow / Joji Ishikawa and Kazuomi Kario
First evaluation 14 Apr 2008 | Latest evaluation 3 Jun 2008
 
6
Exceptional
F1000 Factor 10.5
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
Controversial
Refutation
 Intensity of renal support in critically ill patients with acute kidney injury.
VA/NIH Acute Renal Failure Trial Network, Palevsky PM, …, Star RA, Peduzzi P
N Engl J Med 2008 Jul 3 359(1):7-20 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Achim Joerres / Andrew Davenport / John Laffey / Greg Martin / Arrigo Schieppati and Giuseppe Remuzzi / Heleen Oudemans-van Straaten / William Mitch
First evaluation 2 Jun 2008 | Latest evaluation 14 Aug 2008
 
7
Exceptional
F1000 Factor 10.4
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
Controversial
 Effects of intensive blood-pressure control in type 2 diabetes mellitus.
ACCORD Study Group, Cushman WC, …, Gerstein HC, Ismail-Beigi F
N Engl J Med 2010 Apr 29 362(17):1575-85 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Barit and Mark Cooper / Ihab Wahba / Kirstin Wingler and Harald HHW Schmidt / Enyu Imai / William Mitch / Rebbeca Grysiewicz, Fernando Testai and Philip Gorelick
First evaluation 26 Mar 2010 | Latest evaluation 21 Jun 2010
 
8
Exceptional
F1000 Factor 10.3
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
 Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
CRASH-2 trial collaborators
Lancet 2010 Jun 14 376 [abstract on PubMed] [related articles]
Selected by | Jerrold Levy / Patrick Ray / Julia Neely and Alain Vuylsteke / Nicola Latronico / Greg Martin / Stefania Scimbanassi and Osvaldo Chiara
Dissenters | Nicolas Bruder
First evaluation 21 Jun 2010 | Latest evaluation 17 Aug 2010

 
9
Exceptional
F1000 Factor 10.2

Confirmation
New Finding
Controversial
Refutation
 Stenting versus endarterectomy for treatment of carotid-artery stenosis.
Brott TG, Hobson RW, …, Meschia JF, CREST Investigators
N Engl J Med 2010 Jul 1 363(1):11-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Norman Hertzer / Zirka H Anastasian and Eric Heyer / Sunil Kumar and Sripal Bangalore / Bo Norrving / Philippa Newfield
First evaluation 21 Jun 2010 | Latest evaluation 2 Aug 2010
 
10
Exceptional
F1000 Factor 10.2

Hypothesis
New Finding
 Circulating mitochondrial DAMPs cause inflammatory responses to injury.
Zhang Q, Raoof M, …, Itagaki K, Hauser CJ
Nature 2010 Mar 4 464(7285):104-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Shafer / Michael Fessler / Gerard Curley and John Laffey / Helena Tlaskalova-Hogenova / Walter Hasibeder
First evaluation 25 Mar 2010 | Latest evaluation 6 Jul 2010


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