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  Sections Covered
Breast Diseases: Benign & Malignant
Cancer in the Elderly
Genitourinary Cancers
Gynecological Cancers
Head & Neck Cancers
Oncology Agents
Pediatric Oncology
Sarcomas
Supportive & Palliative Cancer Care
Related Sections
Adrenal Cortex
Gastrointestinal Cancers
Leukemia & Proliferative Disorders of Hematic Cells
Lung Cancer
Lymphomas & Myelomas
Multiple Endocrine Disorders & Neoplasias
Neuro-Oncology
Skin Cancers (inc. Melanoma & Lymphoma)


 CURRENT TOP 10 BY F1000 FACTOR | Oncology | calculated on 12 March 2010

"Current Top 10 By F1000 Factors" are generated every day using only papers added to F1000 Medicine over the last 30 days. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 9.0

New Finding
 Tumor self-seeding by circulating cancer cells.
Kim MY, Oskarsson T, …, Norton L, Massagué J
Cell 2009 Dec 24 139(7):1315-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Antonella De Luca and Nicola Normanno
Evaluated 4 Feb 2010
 
2
Must Read
F1000 Factor 6.5

New Finding
Tech Advance
 Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis.
Griffiths CE, Strober BE, …, Menter A, ACCEPT Study Group
N Engl J Med 2010 Jan 14 362(2):118-28 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Yost and Johann Gudjonsson / Grace H Lo and David Hunter / Robert Dawe
First evaluation 4 Feb 2010 | Latest evaluation 4 Mar 2010
 
3
Must Read
F1000 Factor 6.4

Hypothesis
New Finding
 Identification of the cell lineage at the origin of basal cell carcinoma.
Youssef KK, Van Keymeulen A, …, Sotiropoulou PA, Blanpain C
Nat Cell Biol 2010 Mar 12(3):299-305 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Shigeki Inui and Satoshi Itami / Martin Leverkus
First evaluation 22 Feb 2010 | Latest evaluation 8 Mar 2010

 
4
Must Read
F1000 Factor 6.4

Hypothesis
New Finding
Tech Advance
 Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.
Delaney C, Heimfeld S, …, Manger RL, Bernstein ID
Nat Med 2010 Feb 16(2):232-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | B G Solheim / Patricia Benveniste and Juan Carlos Zuniga-Pflucker
First evaluation 4 Feb 2010 | Latest evaluation 5 Mar 2010
 
5
Must Read
F1000 Factor 6.4
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
Tech Advance
 Preoperative biliary drainage for cancer of the head of the pancreas.
van der Gaag NA, Rauws EA, …, Bossuyt PM, Gouma DJ
N Engl J Med 2010 Jan 14 362(2):129-37 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Claudio Bassi / Atul Kumar
First evaluation 15 Feb 2010 | Latest evaluation 25 Feb 2010
 
6
Must Read
F1000 Factor 6.4

Confirmation
New Finding
 Melanocytic Tumors of Uncertain Malignant Potential: Results of a Tutorial Held at the XXIX Symposium of the International Society of Dermatopathology in Graz, October 2008.
Cerroni L, Barnhill R, …, Rosai J, Kerl H
Am J Surg Pathol 2010 Jan 20 [abstract on PubMed] [related articles] [full text]
Selected by | Giuliana Crisman and Gerardo Ferrara / J Andrew Carlson
First evaluation 4 Feb 2010 | Latest evaluation 17 Feb 2010
 
7
Must Read
F1000 Factor 6.0

New Finding
 Does Helicobacter pylori eradication therapy for peptic ulcer prevent gastric cancer?
Mabe K, Takahashi M, …, Takeda H, Kawata S
World J Gastroenterol 2009 Sep 14 15(34):4290-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Seiji Shiota and Yoshio Yamaoka
Evaluated 8 Mar 2010
 
8
Must Read
F1000 Factor 6.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
 Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: a meta-analysis of 1,640 patients.
Gastrointestinal Stromal Tumor Meta-Analysis Group (metaGIST)
J Clin Oncol 2010 Mar 1 28:1247-53 [abstract on PubMed] [related articles] [order article]
Selected by | Florence Duffaud
Evaluated 8 Mar 2010
 
9
Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland.
Beleut M, Rajaram RD, …, Schneider P, Brisken C
Proc Natl Acad Sci U S A 2010 Feb 16 107(7):2989-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Chellakkan Selvanesan Blesson
Evaluated 4 Mar 2010
 
10
Must Read
F1000 Factor 6.0

New Finding
 Abnormal serum free light chain ratio in patients with multiple myeloma in complete remission has strong association with the presence of oligoclonal bands: implications for stringent complete remission definition.
de Larrea CF, Cibeira MT, …, Yagüe J, Bladé J
Blood 2009 Dec 3 114(24):4954-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Herbaux and Xavier Leleu
Evaluated 4 Mar 2010

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