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Breast Diseases: Benign & Malignant
Cancer in the Elderly
Genitourinary Cancers
Gynecological Cancers
Head & Neck Cancers
Oncology Agents
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Adrenal Cortex
Gastrointestinal Cancers
Leukemia & Proliferative Disorders of Hematic Cells
Lung Cancer
Lymphomas & Myelomas
Multiple Endocrine Disorders & Neoplasias
Neuro-Oncology
Skin Cancers (inc. Melanoma & Lymphoma)


 CURRENT TOP 10 BY F1000 FACTOR | Oncology | calculated on 21 March 2010

"Current Top 10 By F1000 Factors" are generated every day using only papers added to F1000 Medicine over the last 30 days. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
Tech Advance
 Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.
Bienvenu F, Jirawatnotai S, …, Gygi SP, Sicinski P
Nature 2010 Jan 21 463(7279):374-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Chunyu Wang
Evaluated 15 Mar 2010

 
2
Must Read
F1000 Factor 6.5

New Finding
Tech Advance
 Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis.
Griffiths CE, Strober BE, …, Menter A, ACCEPT Study Group
N Engl J Med 2010 Jan 14 362(2):118-28 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Yost and Johann Gudjonsson / Grace H Lo and David Hunter / Robert Dawe
First evaluation 4 Feb 2010 | Latest evaluation 4 Mar 2010
 
3
Must Read
F1000 Factor 6.4

Hypothesis
New Finding
 Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study.
Olmos D, Postel-Vinay S, …, de Bono JS, Haluska P
Lancet Oncol 2010 Feb 11(2):129-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Thomas / Alberto Pappo
First evaluation 11 Jan 2010 | Latest evaluation 16 Mar 2010
 
4
Must Read
F1000 Factor 6.4

Hypothesis
New Finding
 Identification of the cell lineage at the origin of basal cell carcinoma.
Youssef KK, Van Keymeulen A, …, Sotiropoulou PA, Blanpain C
Nat Cell Biol 2010 Mar 12(3):299-305 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Shigeki Inui and Satoshi Itami / Martin Leverkus
First evaluation 22 Feb 2010 | Latest evaluation 8 Mar 2010

 
5
Must Read
F1000 Factor 6.4

Hypothesis
New Finding
Tech Advance
 Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.
Delaney C, Heimfeld S, …, Manger RL, Bernstein ID
Nat Med 2010 Feb 16(2):232-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | B G Solheim / Patricia Benveniste and Juan Carlos Zuniga-Pflucker
First evaluation 4 Feb 2010 | Latest evaluation 5 Mar 2010
 
6
Must Read
F1000 Factor 6.4
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
Tech Advance
 Preoperative biliary drainage for cancer of the head of the pancreas.
van der Gaag NA, Rauws EA, …, Bossuyt PM, Gouma DJ
N Engl J Med 2010 Jan 14 362(2):129-37 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Claudio Bassi / Atul Kumar
First evaluation 15 Feb 2010 | Latest evaluation 25 Feb 2010
 
7
Must Read
F1000 Factor 6.4

Confirmation
New Finding
 Melanocytic Tumors of Uncertain Malignant Potential: Results of a Tutorial Held at the XXIX Symposium of the International Society of Dermatopathology in Graz, October 2008.
Cerroni L, Barnhill R, …, Rosai J, Kerl H
Am J Surg Pathol 2010 Jan 20 [abstract on PubMed] [related articles] [full text]
Selected by | Giuliana Crisman and Gerardo Ferrara / J Andrew Carlson
First evaluation 4 Feb 2010 | Latest evaluation 17 Feb 2010
 
8
Must Read
F1000 Factor 6.0

New Finding
 Secretin inhibits cholangiocarcinoma growth via dysregulation of the cAMP-dependent signaling mechanisms of secretin receptor.
Onori P, Wise C, …, Dostal DE, Glaser SS
Int J Cancer 2009 Nov 10 [abstract on PubMed] [related articles] [full text]
Selected by | Mellanie White and Gianfranco Alpini
Evaluated 19 Mar 2010
 
9
Must Read
F1000 Factor 6.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
 Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations:a nested case-control study.
Jenab M, Bueno-de-Mesquita HB, …, Hainaut P, Riboli E
BMJ 2010 340:b5500 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Robyn Lucas
Evaluated 18 Mar 2010
 
10
Must Read
F1000 Factor 6.0

New Finding
 Impact of proto-oncogene mutation detection in cytological specimens from thyroid nodules improves the diagnostic accuracy of cytology.
Cantara S, Capezzone M, …, Montanaro A, Pacini F
J Clin Endocrinol Metab 2010 Mar 95(3):1365-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Llanyee Liwanpo and Jerome Hershman
Evaluated 18 Mar 2010

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