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Must Read
F1000 Factor 6.0

New Finding
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema.
Yoshida T, Mett I, …, Feinstein E, Tuder RM
Nat Med 2010 Jul 16(7):767-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Takahiro Nakajima and Caroline Owen
Evaluated 27 Aug 2010

Recommended
F1000 Factor 3.2

New Finding
Outcomes in patients with chronic obstructive pulmonary disease and obstructive sleep apnea: the overlap syndrome.
Marin JM, Soriano JB, …, Boldova A, Celli BR
Am J Respir Crit Care Med 2010 Aug 1 182(3):325-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rob Basner / James A Rowley
First evaluation 26 Aug 2010 | Latest evaluation 31 Aug 2010

Recommended
F1000 Factor 3.0

Hypothesis
Controversial
Standard versus newer antibacterial agents in the treatment of severe acute exacerbation of chronic obstructive pulmonary disease: a randomized trial of trimethoprim-sulfamethoxazole versus ciprofloxacin.
Nouira S, Marghli S, …, Elatrous S, Abroug F
Clin Infect Dis 2010 Jul 15 51(2):143-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sergey Yakushin and Roman Kozlov
Evaluated 5 Aug 2010

Must Read
F1000 Factor 6.0

New Finding
Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium.
Donohue JF, Fogarty C, …, Kramer B, INHANCE Study Investigators
Am J Respir Crit Care Med 2010 Jul 15 182(2):155-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ronald Sorkness
Evaluated 4 Aug 2010

Must Read
F1000 Factor 6.0

New Finding
Efficacy of a new once-daily long-acting inhaled beta2-agonist indacaterol versus twice-daily formoterol in COPD.
Dahl R, Chung KF, …, Kramer B, INVOLVE (INdacaterol: Value in COPD: Longer Term Validation of Efficacy and Safety) Study Investigators
Thorax 2010 Jun 65(6):473-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ronald Sorkness
Evaluated 4 Aug 2010

Recommended
F1000 Factor 3.0

Confirmation
Additive effects of transdermal tulobuterol to inhaled tiotropium in patients with COPD.
Ichinose M, Seyama K, …, Kubo K, Beta-2 Agonist Research and Evaluation Committee in COPD (BAREC) Study Group
Respir Med 2010 Feb 104(2):267-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tetsu Kobayashi and Hajime Takizawa
Evaluated 28 Jul 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Validity and reliability of the Schamroth sign for the diagnosis of clubbing.
Pallarés-Sanmartín A, Leiro-Fernández V, …, Botana-Rial M, Fernández-Villar A
JAMA 2010 Jul 14 304(2):159-61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lars Huber
Evaluated 27 Jul 2010

Recommended
F1000 Factor 3.0

New Finding
Hemodynamic and gas exchange effects of sildenafil in patients with chronic obstructive pulmonary disease and pulmonary hypertension.
Blanco I, Gimeno E, …, Roca J, Barberà JA
Am J Respir Crit Care Med 2010 Feb 1 181(3):270-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mike Risbano and Todd Bull
Evaluated 23 Jul 2010

Recommended
F1000 Factor 3.0

New Finding
Inhaled corticosteroid use is associated with lower mortality for subjects with chronic obstructive pulmonary disease and hospitalized with pneumonia.
Malo de Molina R, Mortensen EM, …, Pugh MJ, Anzueto A
Eur Respir J 2010 Apr 22 [abstract on PubMed] [related articles] [full text]
Selected by | Anant Patel and Jadwiga Wedzicha
Evaluated 14 Jul 2010

Recommended
F1000 Factor 3.0

New Finding
Genetic Ancestry in Lung-Function Predictions.
Kumar R, Seibold MA, …, Liu K, Burchard EG
N Engl J Med 2010 [full text]
Selected by | Rob Basner
Evaluated 13 Jul 2010


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