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Acute Renal Failure
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Hemodynamics, Vasc. Biology & Hypertension Sec. to Kidney Dis.
Hereditary, Genetic & Developmental Aspects of Nephrology
Mineral Metabolism & the Kidney
Pathophysiology of Chronic Kidney Disease (CKD)
Renal Function & Transport Physiology
Renal Immunology & Pathology (inc. Glomerular Diseases)
Tubulo-Interstitial Diseases of the Kidney
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Browse > Nephrology > Hereditary, Genetic & Developmental Aspects of Nephrology
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Must Read
F1000 Factor 6.0

New Finding
 Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network.
Aiden AP, Rivera MN, …, Haber DA, Bernstein BE
Cell Stem Cell 2010 Jun 4 6(6):591-602 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Emma Baker, Alanna Green and Louise Purton
Evaluated 27 Aug 2010

Recommended
F1000 Factor 3.0

New Finding
 SLC4A11 prevents osmotic imbalance leading to corneal endothelial dystrophy, deafness, and polyuria.
Gröger N, Fröhlich H, …, Braun T, Boettger T
J Biol Chem 2010 May 7 285(19):14467-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christie Thomas
Evaluated 18 Aug 2010

Recommended
F1000 Factor 3.0

Refutation
 The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo.
Christ A, Terryn S, …, Hammes A, Willnow TE
Kidney Int 2010 Jun 9 [abstract on PubMed] [related articles] [full text]
Selected by | Jenny Lu and Vladimir Marshansky
Evaluated 12 Aug 2010

Exceptional
F1000 Factor 8.2

New Finding
 Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans.
Genovese G, Friedman DJ, …, Pays E, Pollak MR
Science 2010 Aug 13 329(5993):841-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Sedor / Krzysztof Kiryluk / Jochen Reiser
First evaluation 10 Aug 2010 | Latest evaluation 16 Aug 2010


Exceptional
F1000 Factor 9.0

New Finding
 Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis.
Novarino G, Weinert S, Rickheit G, Jentsch TJ
Science 2010 Jun 11 328(5984):1398-401 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gustavo Ares and Pablo Ortiz
Evaluated 4 Aug 2010


Must Read
F1000 Factor 6.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
 Genotype-phenotype correlation in X-linked Alport syndrome.
Bekheirnia MR, Reed B, …, Masoumi A, Schrier RW
J Am Soc Nephrol 2010 May 21(5):876-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nine Knoers
Evaluated 2 Aug 2010

Must Read
F1000 Factor 4.8

New Finding
Refutation
 Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease.
Walz G, Budde K, …, Kramer S, Eckardt KU
N Engl J Med 2010 Jun 26 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Albert Ong / Fiona Karet
First evaluation 29 Jul 2010 | Latest evaluation 4 Aug 2010

Must Read
F1000 Factor 6.4

New Finding
Refutation
 Sirolimus and Kidney Growth in Autosomal Dominant Polycystic Kidney Disease.
Serra AL, Poster D, …, Weishaupt D, Wüthrich RP
N Engl J Med 2010 Jun 26 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Arrigo Schieppati and Giuseppe Remuzzi / Albert Ong
First evaluation 19 Jul 2010 | Latest evaluation 29 Jul 2010

Must Read
F1000 Factor 6.0

Tech Advance
 Novel siRNA delivery system to target podocytes in vivo.
Hauser PV, Pippin JW, …, Alpers CE, Shankland SJ
PLoS One 2010 5(3):e9463 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Luigi Gnudi
Evaluated 19 Jul 2010

Must Read
F1000 Factor 6.0

New Finding
 Vitamin D receptor attenuates renal fibrosis by suppressing the renin-angiotensin system.
Zhang Y, Kong J, …, Chang A, Li YC
J Am Soc Nephrol 2010 Jun 21(6):966-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Antonio Seguro
Evaluated 16 Jul 2010


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