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F1000 Factor 3.0

Hypothesis
Osteoblasts and bone marrow mesenchymal stromal cells control hematopoietic stem cell migration and proliferation in 3D in vitro model.
de Barros AP, Takiya CM, …, Borojevic R, Rossi MI
PLoS One 2010 5(2):e9093 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Fatima Saleh and Paul Genever
Evaluated 11 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: implications for the treatment of myeloproliferative neoplasms.
Quintás-Cardama A, Vaddi K, …, Fridman JS, Verstovsek S
Blood 2010 Feb 3 [abstract on PubMed] [related articles] [full text]
Selected by | Stephen Oh and Jason Gotlib
Evaluated 3 Mar 2010

Must Read
F1000 Factor 4.8

New Finding
Systemic signals regulate ageing and rejuvenation of blood stem cell niches.
Mayack SR, Shadrach JL, Kim FS, Wagers AJ
Nature 2010 Jan 28 463(7280):495-500 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yoshiko Matsumoto and Toshio Suda / Nelson Chao
First evaluation 3 Mar 2010 | Latest evaluation 5 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
Comparative assessment of telomere length before and after hematopoietic SCT: role of grafted cells in determining post-transplant telomere status.
Ruella M, Rocci A, …, Corradini P, Tarella C
Bone Marrow Transplant 2009 Oct 19 [abstract on PubMed] [related articles] [full text]
Selected by | Shahinaz Gadalla and Sharon Savage
Evaluated 26 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution.
Lewandowski D, Barroca V, …, Tavitian B, Roméo PH
Blood 2010 Jan 21 115(3):443-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Halvard Bönig and Thalia Papayannopoulou
Evaluated 24 Feb 2010

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients.
Agarwal S, Loh YH, …, Liu L, Daley GQ
Nature 2010 Feb 17 [abstract on PubMed] [related articles] [full text]
Selected by | Philip J Mason and Monica Bessler
Evaluated 24 Feb 2010

Must Read
F1000 Factor 4.8

New Finding
Tech Advance
Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential.
Benveniste P, Frelin C, …, Hyam D, Iscove NN
Cell Stem Cell 2010 Jan 8 6(1):48-58 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christoph Schaniel and Kateri Moore / David L Stachura and David Traver
First evaluation 24 Feb 2010 | Latest evaluation 25 Feb 2010


Must Read
F1000 Factor 6.0

New Finding
Hematopoietic stem cell development is dependent on blood flow.
North TE, Goessling W, …, Dzierzak E, Zon LI
Cell 2009 May 15 137(4):736-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ben van Handel and Hanna Mikkola
Evaluated 19 Feb 2010


Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Reexposure of cord blood to noninherited maternal HLA antigens improves transplant outcome in hematological malignancies.
van Rood JJ, Stevens CE, …, Carpenter C, Scaradavou A
Proc Natl Acad Sci U S A 2009 Nov 24 106(47):19952-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Effie Petersdorf
Evaluated 10 Feb 2010

Must Read
F1000 Factor 6.0

New Finding
Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupus.
Zhang L, Bertucci AM, …, Burt RK, Datta SK
J Immunol 2009 Nov 15 183(10):6346-58 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vaidehi R Chowdhary and Ann Reed
Evaluated 10 Feb 2010



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