Ralf Paus

Dept of Dermatology, University Hospital Schleswig-Holstein, Germany

Academic positions: Professor of Dermatology and experimental dermatology, University Hospital Schleswig-Holstein, University of Lubeck Visiting Professor at Dept. Molecular Medicine, Max-Planck Institute for Biochemistry, Munich Visiting Professor at Dept. Biomedical Sciences, University of Bradford, UK

All commercial positions (in last five years): Member of HSF Medical and Scientific advisory Board Consultant for Beiersdorf (Germany), Schering (Germany), Symrise (USA), Associate Editor of Experimental Dermatology and Journal of investigative dermatology Reviewer for numerous, leading dermatological and life science journals

Previous positions (in the last five years): 1999-2004 Professor and Vice-Chair Dept. of Dermatology, University Hospital Eppendorf, University of Hamburg 1-6/2005 – Sabbatical, Dept. Molecular Medicine, Max-Planck Institute for Biochemistry, Munich

Research interests: Neurobiology, Neuroendocrinology and neuroimmunology or the skin Hair follicle biology Regeneratrive medicine Biology of the nail apparatus Development of novel in vitro screening assays for candidate skin and hair drugs

 Any other information: Languages – German, English Italian

 

Any competing interests declared are displayed with individual evaluations.

Section Head: Dermatology > Hair Diseases (since 22 November 2005)

Ralf Paus is a Section Head for Hair Diseases, part of the DERMATOLOGY Faculty. The role of a Section Head is to work with their Co-Section Head(s) to divide the Section (sub-specialty area) into its component areas of research, nominate leaders in those areas as Faculty Members, and offer ongoing oversight of the content within their Section. They are not asked to evaluate articles, although we do, of course, welcome them.

All recent recommendations

• 6.0
  Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis.
  Recommended by Ralf Paus with Natalia Meier, Jennifer Klatte
  
• 6.0
  Identification of novel hair-growth inducers by means of connectivity mapping.
  Recommended by Ralf Paus with Koji Sugawara, Jennifer Klatte
  
• 3.0
  BMP signaling induces cell-type-specific changes in gene expression programs of human keratinocytes and fibroblasts.
  Recommended by Ralf Paus
  
• 3.0
  Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation.
  Recommended by Ralf Paus with Katja Meyer, Jennifer Klatte
  
• 3.0
  The Suppressor of Cytokine Signaling (SOCS)-3 determines keratinocyte proliferative and migratory potential during skin repair.
  Recommended by Ralf Paus with Koji Sugawara, Jennifer Klatte
  
• 4.8
  Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model.
  Recommended by Ralf Paus with Koji Sugawara, Jennifer Klatte, Amos Gilhar
  
• 3.0
  The human antimicrobial peptide LL-37 suppresses apoptosis in keratinocytes.
  Recommended by Ralf Paus with Jennifer Klatte
  
• 6.0
  Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral-nerve injury: an advantageous alternative to ES and iPS cells.
  Recommended by Ralf Paus with Stephan Tiede, Jennifer Klatte
  
• 3.0
  Molecular clocks in mouse skin.
  Recommended by Ralf Paus with Jennifer Klatte
  
• 3.0
  Human beta-defensin-2 and psoriasin are overexpressed in lesions of acne inversa.
  Recommended by Ralf Paus with Jennifer Klatte and Katja C Meyer
  
• 8.0
  Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation.
  Recommended by Ralf Paus with Elisabeth Gaspar, Jennifer Klatte, Stephan Tiede, Burkhard Poeggeler, Desmond Tobin
  
• 6.0
  Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis.
  Recommended by Ralf Paus with Jennifer Klatte
  
• 6.0
  Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling.
  Recommended by Ralf Paus with Jennifer Klatte and Yuval Ramot
  
• 6.0
  Expression of a functional epidermal growth factor receptor on human adipose-derived mesenchymal stem cells and its signaling mechanism.
  Recommended by Ralf Paus with Jennifer Klatte
  
• 6.0
  Anandamide regulates keratinocyte differentiation by inducing DNA methylation in a CB1 receptor-dependent manner.
  Recommended by Ralf Paus with Koji Sugawara and Jennifer Klatte
  
• 8.0
  5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.
  Recommended by Zhu Chen with Jiang Zhu, Ralf Paus with Jennifer Klatte, Yuval Ramot, Burkhard Poeggeler, Natlia Maier
  
• 9.0
  Generation of human induced pluripotent stem cells from dermal fibroblasts.
  Recommended by Ralf Paus with Burkhard Poeggeler, Jennifer Klatte, Yuval Ramot and Stephan Tiede
  
• 9.0
  Liposomal packaging generates Wnt protein with in vivo biological activity.
  Recommended by Ralf Paus with Jennifer Klatte, Burkhard Poeggeler, Yuval Ramot and Stephan Tiede
  
• 3.0
  Lysophospholipid Receptor-Mediated Calcium Signaling in Human Keratinocytes.
  Recommended by Ralf Paus with Tobias Fischer and Koji Sugawara
  
• 3.0
  Morphometry of human terminal and vellus hair follicles.
  Recommended by Ralf Paus with Tobias Fischer
  
• 3.0
  Investigation of the hair follicle inner root sheath in scarring and non-scarring alopecia.
  Recommended by Ralf Paus with Tobias Fischer and Matthew Harries